| 摘要 |
<p>The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.</p> |
| 申请人 |
MERCK SHARP & DOHME CORP.;HAGMANN, WILLIAM K.;LI, BING;SZEWCZYK, JASON W.;WANG, BOWEI;PARKER, DANN;BLIZZARD, TIMOTHY;JOSIEN, HUBERT;BIJU, PURAKKATTLE;CHOBANIAN, HARRY;GUDE, CANDIDO;NARGUND, RAVI P.;PIO, BARBARA;DANG, QUN;LIN, LINUS S.;HU, BIN;CUI, MINGXIANG;CHEN, ZHENGXIA;DAI, MEIBI;ZHANG, ZAIHONG;LV, YING;TIAN, LILI |
发明人 |
HAGMANN, WILLIAM K.;LI, BING;SZEWCZYK, JASON W.;WANG, BOWEI;PARKER, DANN;BLIZZARD, TIMOTHY;JOSIEN, HUBERT;BIJU, PURAKKATTLE;CHOBANIAN, HARRY;GUDE, CANDIDO;NARGUND, RAVI P.;PIO, BARBARA;DANG, QUN;LIN, LINUS S.;HU, BIN;CUI, MINGXIANG;CHEN, ZHENGXIA;DAI, MEIBI;ZHANG, ZAIHONG;LV, YING;TIAN, LILI |
