发明名称 DOSAGE AND ADMINISTRATION OF BISPECIFIC SCFV CONJUGATES
摘要 <p>Disclosed are methods for the therapeutic administration of bispecific scFv conjugates as single doses at at least weekly intervals. In certain embodiments the conjugate is MM-111 and is administered at intervals of every two weeks or every three weeks. In other embodiments a single loading dose of MM-111 is administered to a human patient followed at at least weekly intervals by a least a single maintenance dose of MM-111. The loading dose is larger than the maintenance dose.</p>
申请公布号 EP2648753(A4) 申请公布日期 2015.06.24
申请号 EP20110847515 申请日期 2011.12.12
申请人 MERRIMACK PHARMACEUTICALS, INC. 发明人 MCDONAGH, CHARLOTTE;GIBBONS, FRANCIS;MOYO, VICTOR
分类号 A61K39/395;A61K47/48 主分类号 A61K39/395
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