发明名称 PYRAZOLYL-UREAS AS KINASE INHIBITORS
摘要 There are provided compounds of formula I, wherein R, R1, Ra, Rb, Q, X and Y have meanings given in the description, which compounds have antiinflammatory activity (e.g., through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
申请公布号 EP2885284(A1) 申请公布日期 2015.06.24
申请号 EP20130750934 申请日期 2013.08.16
申请人 RESPIVERT LIMITED;TOPIVERT PHARMA LIMITED 发明人 CARIOU, CLAIRE, ANNE, MARIE;CHARRON, CATHERINE, ELISABETH;FORDYCE, EUAN, ALEXANDER, FRASER;HAMZA, DANIEL;FYFE, MATTHEW, COLIN, THOR;ITO, KAZUHIRO;KING-UNDERWOOD, JOHN;MURRAY, PETER, JOHN;ONIONS, STUART, THOMAS;THOM, STEPHEN, MALCOLM;WATSON, HAYLEY, TEGAN, ANGELA;WILLIAMS, JONATHAN, GARETH
分类号 C07D401/12;A61K31/4155;A61K31/506;A61P11/00;A61P29/00;A61P31/16;C07D401/14;C07D403/12 主分类号 C07D401/12
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