发明名称 |
PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION |
摘要 |
<p>An object of the present invention is to provide a carrier composition for nucleic acid delivery, which can efficiently deliver a nucleic acid into cells when a nucleic acid such as siRNA is administered to animal-derived cells or animals, and also has low toxicity and high safety, and a composition for nucleic acid delivery containing the carrier composition and nucleic acid. A carrier for nucleic acid delivery is prepared by using (A) a diacylphosphatidylcholine, (B) at least one member selected from the group consisting of cholesterol and derivatives thereof, and (C) an aliphatic primary amine. Also, a composition for nucleic acid delivery is prepared by mixing the carrier for nucleic acid delivery with a nucleic acid.</p> |
申请公布号 |
EP2140870(B1) |
申请公布日期 |
2015.06.24 |
申请号 |
EP20080738918 |
申请日期 |
2008.03.26 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD.;TAKEUCHI, HIROFUMI |
发明人 |
TAKEUCHI, HIROFUMI;HIRA, YASUYUKI;NAKANO, KOJI;TOYOBUKU, HIDEKAZU |
分类号 |
A61K31/7088;A61K9/127;A61K31/713;A61K47/18;A61K47/24;A61K47/28;A61K48/00 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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