Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases

摘要

The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.

主权项

1. A method of treating dry eye syndrome in a patient, comprising:
administering to said patient a therapeutic agent comprising TSG-6 protein or a biologically active fragment, or variant thereof, wherein said TSG-6 protein or biologically active fragment, or variant thereof, is administered in an amount effective to treat said dry eye syndrome in said patient.