Apparatus for health correlation assessment

摘要

An apparatus, system and method for performing a health correlation assessment based upon results an eye contrast sensitivity measurement test of a person. The health correlation assessment yields a predictive and probabilistic measure of the likelihood of the person appropriately assigned to a particular clinical health classification. Such an eye contrast sensitivity measurement can be used to identify people who are likely to be within a pre-Alzheimer's disease state or within Alzheimer's disease state of health and identify those who should seek further clinical and/or other types of testing to ascertain their actual health status and to determine an appropriate course of medical treatment.

主权项

1. An apparatus for performing a probabilistic assessment for one or more Alzheimer's disease related clinical health classifications based upon results of a contrast sensitivity eye examination test, comprising:
an eye contrast sensitivity testing device that is configured to perform an eye contrast sensitivity test with respect to a first subject, and that is further configured to generate eye contrast sensitivity test result data, representing a result of said eye contrast sensitivity test with respect to said first subject; a data access component for obtaining at least a portion of eye contrast sensitivity test result data from a first eye contrast sensitivity test performed by a first subject, from said eye contrast sensitivity testing device; a health correlation assessment component that exercises a first algorithm in accordance with a correlation model, that includes exercise of a set of one or more mathematical equations that are each is applied to process said at least a portion of eye contrast sensitivity test result data of said first eye contrast sensitivity test, each of said first set of equations including a separate variable representing a numerical probability value associated with a separate probabilistic health classification, each said component outputs at least one numerical probability value representing an estimated probability of said first subject being clinically assigned into at least one of a plurality of Alzheimer's disease related health classifications, said health classifications including at least one classification indicating a presence of an Alzheimer's disease related abnormality within said first subject; said first set of equations each employing a set of at least two mathematical coefficients, said coefficients each being a numerical value that is determined by exercise of a second algorithm configured for processing a repository of data in accordance with a correlation model, said repository of data including other eye contrast sensitivity test result data obtained from eye contrast sensitivity tests performed by subjects other than said first subject; and an output component that outputs information representing said probabilistic health classifications.