发明名称 |
Bone delivery device |
摘要 |
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. |
申请公布号 |
US9061075(B2) |
申请公布日期 |
2015.06.23 |
申请号 |
US200711900776 |
申请日期 |
2007.09.12 |
申请人 |
THE INVENTION SCIENCE FUND I, LLC |
发明人 |
Harlow Ed;Jung Edward K. Y.;Langer Robert;Leuthardt Eric C.;Wood, Jr. Lowell L. |
分类号 |
C12N5/00;C12N5/02;C12N11/00;C12N11/16;A61K47/48;A61K9/00;C12N5/077;A61K35/12 |
主分类号 |
C12N5/00 |
代理机构 |
Dorsey & Whitney LLP |
代理人 |
Dorsey & Whitney LLP |
主权项 |
1. A method of assembling an implantable device for delivering one or more biologically active molecules to a subject, comprising:
identifying the one or more biologically active molecules, selecting one or more devices at least partially constructed of anorganic bone and including a natural internal cavity therein; micromachining the one or more devices to re-shape the natural internal cavity thereof; micromachining the one or more devices to form one or more openings therein; providing the one or more biologically active molecules to the one or more devices; and closing the one or more openings with a layer of confluent cells prior to implanting the device in the subject. |
地址 |
Bellevue WA US |