发明名称 Bone delivery device
摘要 Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.
申请公布号 US9061075(B2) 申请公布日期 2015.06.23
申请号 US200711900776 申请日期 2007.09.12
申请人 THE INVENTION SCIENCE FUND I, LLC 发明人 Harlow Ed;Jung Edward K. Y.;Langer Robert;Leuthardt Eric C.;Wood, Jr. Lowell L.
分类号 C12N5/00;C12N5/02;C12N11/00;C12N11/16;A61K47/48;A61K9/00;C12N5/077;A61K35/12 主分类号 C12N5/00
代理机构 Dorsey & Whitney LLP 代理人 Dorsey & Whitney LLP
主权项 1. A method of assembling an implantable device for delivering one or more biologically active molecules to a subject, comprising: identifying the one or more biologically active molecules, selecting one or more devices at least partially constructed of anorganic bone and including a natural internal cavity therein; micromachining the one or more devices to re-shape the natural internal cavity thereof; micromachining the one or more devices to form one or more openings therein; providing the one or more biologically active molecules to the one or more devices; and closing the one or more openings with a layer of confluent cells prior to implanting the device in the subject.
地址 Bellevue WA US