发明名称 |
Multilead ECG template-derived residua for arrhythmia risk assessment |
摘要 |
A method and system for predicting the onset of heart arrhythmias more accurately observes trends in abnormal or pathologic morphology of the electrocardiogram (ECG). A first set of ECG signals is monitored from a patient. A baseline measurement is generated from the monitored first set of ECG signals to contain nonpathologic ECG morphologies in each lead. A second set of ECG signals is monitored from the patient and the baseline measurement is subtracted from the second set of ECG signals on a beat-to-beat basis. Afterwards, a residuum signal is generated for each lead based on the subtraction. R-wave heterogeneity, T-wave heterogeneity, P-wave heterogeneity, or ST-segment heterogeneity or other indicators of arrhythmia risk or myocardial ischemia are quantified based on the generated residuum signals. |
申请公布号 |
US9060699(B2) |
申请公布日期 |
2015.06.23 |
申请号 |
US201213624544 |
申请日期 |
2012.09.21 |
申请人 |
Beth Israel Deaconess Medical Center, Inc. |
发明人 |
Nearing Bruce D.;Verrier Richard L. |
分类号 |
A61B5/0452;A61B5/04;A61B5/0472;A61B5/00;A61B5/0456 |
主分类号 |
A61B5/0452 |
代理机构 |
Sterne, Kessler, Goldstein & Fox P.L.L.C. |
代理人 |
Sterne, Kessler, Goldstein & Fox P.L.L.C. |
主权项 |
1. A method of quantifying risk of cardiac arrhythmia, comprising:
receiving a first set of electrocardiogram (ECG) signals from spatially separated leads; generating a baseline beat template associated with the morphology of each ECG signal of the first set of ECG signals; receiving a second set of ECG signals from spatially separated leads; calculating, for each lead, a difference between each ECG signal in the second set of ECG signals and the corresponding baseline beat template to produce a residuum signal for each lead; averaging the residuum signals across the leads to produce an averaged residuum signal; and quantifying a spatio-temporal heterogeneity of the second set of ECG signals based on the residuum signals and the averaged residuum signal, wherein the spatio-temporal heterogeneity is associated with arrhythmia risk. |
地址 |
Boston MA US |