| 发明名称 | Process for producing imide compound | ||
| 摘要 | The present invention provides an excellent industrial process for producing an imide compound hydrochloride.;The process for producing an imide compound hydrochloride of the formula (2):; or an enantiomer thereof, which comprises treating a compound of the formula (1): ; or an enantiomer thereof with an aqueous hydrochloric acid solution in a hydrophilic solvent, followed by crystallizing the resultant. | ||
| 申请公布号 | USRE45573(E1) | 申请公布日期 | 2015.06.23 |
| 申请号 | US201314137464 | 申请日期 | 2013.12.20 |
| 申请人 | Sumitomo Dainippon Pharma Co., Ltd. | 发明人 | Kakiya Yuzo;Oda Mayumi |
| 分类号 | C07D401/14;C07D241/04;C07D295/00 | 主分类号 | C07D401/14 |
| 代理机构 | Finnegan, Henderson, Farabow, Garrett & Dunner, LLP | 代理人 | Finnegan, Henderson, Farabow, Garrett & Dunner, LLP |
| 主权项 | 1. A process for producing an imide compound hydrochloride of the formula (2):or an enantiomer thereof,which comprises treating a compound of the formula (1):or an enantiomer thereof with 1.8 to 5.0% aqueous hydrochloric acid solution in acetone, crystallizing the resultant hydrochloride of the formula (2), and isolating the crystallized hydrochloride of the formula (2). | ||
| 地址 | Osaka JP | ||