摘要 |
The present disclosure relates to compounds that are Syk inhibitors. In particular embodiments, the structure of the compounds is given by Formula I: (see formula I) wherein R1, R2, R3, and R4 are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions for Syk inhibition. |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
BLOMGREN, PETER A.;MITCHELL, SCOTT A.;CURRIE, KEVIN S.;SCHMITT, AARON C.;KROPF, JEFFREY E.;XIONG, JIN-MING;LEE, SEUNG H.;XU, JIANJUN;LO, JENNIFER R.;ZHAO, ZHONGDONG |