| 发明名称 | HER2Delta16 peptides | ||
| 摘要 | The present invention provides cyclic peptides comprising a dimer of peptides, each peptide comprising a sequence corresponding to the HER2 splice variant HER2Delta16, wherein the cyclic peptide is cyclized via a disulfide bond between the peptides and via an amino acid linking the peptides. The invention also provides methods of making antibodies that specifically bind to HER2Delta16 homodimers using said cyclic peptides. | ||
| 申请公布号 | US9062096(B2) | 申请公布日期 | 2015.06.23 |
| 申请号 | US201313901210 | 申请日期 | 2013.05.23 |
| 申请人 | NESTEC S.A. | 发明人 | Ling Nicholas Chi-Kwan |
| 分类号 | C07K14/71;C07K16/32;C07K7/64 | 主分类号 | C07K14/71 |
| 代理机构 | Kilpatrick Townsend & Stockton LLP | 代理人 | Kilpatrick Townsend & Stockton LLP |
| 主权项 | 1. A cyclic peptide having the structure: wherein MPA is beta-mercaptopropionic acid. | ||
| 地址 | Vevey CH | ||