| 发明名称 | Methods for treating gout flares | ||
| 摘要 | Methods of treating gout flares comprising administering a composition comprising a first urate-lowering agent are disclosed. In some aspects, the first urate-lowering agent is (−)-halofenate, (−)-halofenic acid, or a pharmaceutically acceptable salt thereof. Other aspects provide for methods of reducing the number, duration, frequency or intensity of gout flares experienced by a subject. | ||
| 申请公布号 | US9060987(B2) | 申请公布日期 | 2015.06.23 |
| 申请号 | US201213668003 | 申请日期 | 2012.11.02 |
| 申请人 | CYMABAY THERAPEUTICS, INC. | 发明人 | Lavan Brian Edward;Saha Gopal Chandra;McWherter Charles A.;Roberts Brian K. |
| 分类号 | A61K31/192;A61K31/216;A61K31/426;C07C59/68;C07C233/47 | 主分类号 | A61K31/192 |
| 代理机构 | Hamilton, DeSanctis & Cha, LLP | 代理人 | Nguyen Sam L.;Hamilton, DeSanctis & Cha, LLP |
| 主权项 | 1. A method for decreasing the number, duration, frequency, or intensity of gout flares, experienced by a subject during initiation or maintenance of therapy for uric acid lowering, comprising administration to the subject of a therapeutically effective amount of a flare decreasing agent that is selected from the group consisting of (−)-halofenate and (−)-halofenic acid, or a pharmaceutically acceptable salt thereof, and substantially free from its (+)-enantiomer. | ||
| 地址 | Newark CA US | ||