主权项 |
1. A solid dry powder composition comprising:
(a) an active agent; and (b) a dextran polymer comprising
(i) an ester-linked amine-containing substituent, selected from and mixtures thereof, wherein R1 is selected from C1, C2, C3, or C4 alkyl groups, R2 and R3 may be the same or different and are selected from hydrogen, methyl and ethyl groups, and R4, R5, and R6 may be the same or different and are selected from methyl and ethyl groups, and wherein the degree of substitution of said ester-linked amine-containing substituent is at least 0.03, and(ii) an alkyl ester substituent selected from acetate, propionate, butyrate, isobutyrate, and mixtures thereof, wherein the degree of substitution of said alkyl ester substituent is at least 0.05. |