| 发明名称 |
AZAINDOLE USEFUL AS JAK AND OTHER PROTEIN KINASE INHIBITOR |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a JAK and other protein kinase inhibitor. ! SOLUTION: Provided is a compound of the formula (I) that is an inhibitor of protein kinase. Also provided are a pharmaceutical composition containing said compound and a method for using said composition in the treatment of various disorders. Now said compound and pharmaceutically acceptable composition thereof are found effective as the inhibitor of JAK, ROCK and Aurora protein kinase. In one embodiment, these compounds are effective as inhibitor of JAK, ROCK and Aurora protein kinase. ! COPYRIGHT: (C)2015,JPO&INPIT |
| 申请公布号 |
JP2015113347(A) |
申请公布日期 |
2015.06.22 |
| 申请号 |
JP20150051664 |
申请日期 |
2015.03.16 |
| 申请人 |
VERTEX PHARMACEUTICALS INC |
发明人 |
SALITURO FRANCESCO ; FARMER LUC ; BETHIEL RANDY ; HARRINGTON EDMUND ; GREEN JEREMY ; COURT JOHN ; COME JON ; LAUFFER DAVID ; ARONOV ALEX ; BINCH HAYLEY ; BOYALL DEAN ; CHARRIER JEAN-DAMIEN ; EVERITT SIMON ; FRAYSSE DAMIEN ; MORTIMORE MICHAEL ; PIERARD FRANCOISE ; ROBINSON DANIEL ; WANG JIAN ; PINDER JOANNE ; WANG TIANSHENG ; PIERCE ALBERT |
| 分类号 |
C07D471/04;A61K31/437;A61K31/444;A61K31/4709;A61K31/496;A61K31/506;A61K31/517;A61K31/5377;A61K31/55;A61K31/551;A61K31/695;A61K45/00;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P7/00;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/08;A61P13/12;A61P15/00;A61P15/10;A61P17/00;A61P19/02;A61P19/08;A61P19/10;A61P21/00;A61P25/00;A61P25/28;A61P27/06;A61P29/00;A61P31/00;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/06;A61P37/08;A61P43/00;C07D519/00;C07F7/10 |
主分类号 |
C07D471/04 |
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