SYNTHESIS OF α,, ß-UNSATURATED CARBOXYLIC ACIDS AND ESTERS

摘要

Abstract: Disclosed herein is a cost-effective, environmentally benign, one pot catalytic process for synthesis of a, ß-unsaturated carboxylic acids (2) and esters (2') with high E-stereoselectivity from derivatives of cyclic 1, 3-diesters (Meldrum’s esters) (1) using a highly efficient catalytic protocols containing FeCl3.6H2O (cat.), H2O (1 equiv.) and FeCl3.6H2O (cat.), alcohol (R2-OH, 1 equiv.) in CH3NO2 respectively under microwave irradiation as well as under conventional heating conditions with better turnover number (TON) and turnover frequency (TOF) values.