发明名称 |
Dual variable region antibody-like binding proteins having cross-over binding region orientation |
摘要 |
The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross- over orientation. The invention also provides methods for making such antigen-like binding proteins. |
申请公布号 |
AU2012236603(B2) |
申请公布日期 |
2015.06.18 |
申请号 |
AU20120236603 |
申请日期 |
2012.03.28 |
申请人 |
SANOFI |
发明人 |
BAURIN, NICOLAS;BEIL, CHRISTIAN;CORVEY, CARSTEN;LANGE, CHRISTIAN;LI, DANXI;MIKOL, VINCENT;STEINMETZ, ANKE;RAO, ERCOLE |
分类号 |
C07K16/00;C07K16/24;C07K16/28;C07K16/32;C07K16/46 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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