Stable complexes of an alkaline earth metal salt of N(5) -methyl-tetrahydrofolic acid and a polyol

摘要

Complexes between an alkaline earth metal salt of (6RS)- or (6S)-N 5-methyl (5,6,7,8)-tetrahydrofolic acid and a polyol were prepared by lyophilization or spray drying. These products were found to be stable compared with the active ingredient 5 alone or the mixture of the same components prepared by means of other methodologies. 5948366_1 (GHMatters) P98247.AU DONNAL