Methods and Systems for Analysis of Organ Transplantation

摘要

Disclosed herein are methods of detecting, predicting or monitoring a status or outcome of a transplant in a transplant recipient.

主权项

1. A method of detecting or predicting a condition of a transplant recipient, the method comprising:
a. obtaining a sample, wherein the sample comprises one or more gene expression products from the transplant recipient; b. performing an assay to determine an expression level of the one or more gene expression products from the transplant recipient; and c. detecting or predicting the condition of the transplant recipient by applying an algorithm to the expression level determined in step (b), wherein the algorithm is a classifier capable of distinguishing between at least two conditions that are not normal conditions, wherein one of the at least two conditions is an acute rejection, and wherein one of the at least two conditions is a transplant dysfunction with no rejection.