SYSTEMS AND METHODS FOR INTEGRATING A SINGLE DNA MOLECULE INTO A MOLECULAR ELECTRONIC DEVICE

摘要

The disclosed subject matter provides a techniques for precisely and/or functionally cutting carbon nanotubes, e.g., single walled carbon nanotubes (“SWNTs”) and integrating a single nucleic acid molecule (e.g., a DNA molecule) into a gap formed into the carbon nanotubes. In one aspect, a method of fabricating a molecular electronic device includes disposing a SWNT on a base layer, forming a gap in the SWNT using a lithographic process, and disposing a single DNA strand across the gap so that each end of the nucleic acid contacts a gap termini. The disclosed subject matter also provides techniques for measuring the electrical properties (charge transport) of a DNA molecule which is integrated into an SWNT. Furthermore, a molecular electronic device including an SWNT with an integrated nucleic acid molecule is disclosed.

主权项

1. A method for integrating a single nucleic acid molecule into a molecular electronic device comprising:
(a) disposing a carbon nanotube on a base layer of said molecular electronic device; (b) forming a gap in said carbon nanotube; and (c) bridging said gap with a single nucleic acid molecule.