发明名称 |
SMALL MOLECULE INHIBITORS OF INFLUENZA A RNA-DEPENDENT RNA POLYMERASE |
摘要 |
<p>Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are cellular assays to identify small molecule compounds having antiviral properties, particularly as it relates to detection of influenza A RNA-dependent RNA polymerase activity in a mammalian cell independent of other influenza A components. Preferred assays allow for identification of viral replication inhibitors that do not disrupt normal cellular activity.</p> |
申请公布号 |
WO2015088516(A1) |
申请公布日期 |
2015.06.18 |
申请号 |
WO2013US74415 |
申请日期 |
2013.12.11 |
申请人 |
NANT HOLDINGS IP, LLC |
发明人 |
NIAZI, KAYVAN;RABIZADEH, SHAHROOZ;LE NY, ANNE-LAURE;BUZKO, OLEKSANDR;GOLOVATO, JUSTIN;SOON-SHIONG, PATRICK |
分类号 |
A61K31/437;A61K31/519;A61P31/12;A61P31/16 |
主分类号 |
A61K31/437 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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