CIRCADIAN RHYTHM IMPROVER

摘要

PROBLEM TO BE SOLVED: To provide a circadian rhythm improver and a food and drink or medicine comprising the same, which can prevent or improve/inhibit disorder symptoms or diseases resulting from circadian rhythm disturbance by regulating the amplitude, cycle length and phase of circadian rhythm (expression rhythm of clock gene).SOLUTION: Provided are a circadian rhythm improver and a food and drink or medicine, comprising at least one of a dipeptide compound having an imidazole skeleton such as carnosine and anserine and a pharmaceutically acceptable salt thereof as an active ingredient.