发明名称 FORMULATIONS OF HISTONE DEACETYLASE INHIBITOR AND USES THEROF
摘要 Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include an HDAC inhibitor, or a pharmaceutically acceptable salt thereof, are described.
申请公布号 US2015164854(A1) 申请公布日期 2015.06.18
申请号 US201514620075 申请日期 2015.02.11
申请人 Pharmacyclics, Inc. 发明人 LOURY David J.;BUGGY Joseph J.;MODY Tarak D.;VERNER Erik J.;PURRO Norbert;Balasubramanian Sriram
分类号 A61K31/343;A61K45/06;A61N5/10;A61K38/05 主分类号 A61K31/343
代理机构 代理人
主权项 1. A method of treating cancer in an individual in need thereof comprising orally administering a first dose of an HDAC inhibitor at a first time and orally administering a second dose of the HDAC inhibitor at a second time, wherein an effective plasma concentration of the HDAC inhibitor is maintained for at least 6 consecutive hours.
地址 Sunnyvale CA US