发明名称 |
FORMULATIONS OF HISTONE DEACETYLASE INHIBITOR AND USES THEROF |
摘要 |
Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include an HDAC inhibitor, or a pharmaceutically acceptable salt thereof, are described. |
申请公布号 |
US2015164854(A1) |
申请公布日期 |
2015.06.18 |
申请号 |
US201514620075 |
申请日期 |
2015.02.11 |
申请人 |
Pharmacyclics, Inc. |
发明人 |
LOURY David J.;BUGGY Joseph J.;MODY Tarak D.;VERNER Erik J.;PURRO Norbert;Balasubramanian Sriram |
分类号 |
A61K31/343;A61K45/06;A61N5/10;A61K38/05 |
主分类号 |
A61K31/343 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating cancer in an individual in need thereof comprising orally administering a first dose of an HDAC inhibitor at a first time and orally administering a second dose of the HDAC inhibitor at a second time, wherein an effective plasma concentration of the HDAC inhibitor is maintained for at least 6 consecutive hours. |
地址 |
Sunnyvale CA US |