SEQUENTIAL ADMINISTRATION OF PARTITIONED ABSORPTION ASPIRIN OR ACTIVE ASPIRIN DERIVATIVE AND COX-2 INHIBITOR

摘要

Described herein are an aspirin or active aspirin derivative and a COX-2 inhibitor, at least one of which has an enteric or partial enteric coating, administered in combination yet delivered sequentially, for the treatment and prophylactic treatment of diseases, symptoms and conditions. In some embodiments, the COX-2 inhibitor has the enteric coating; however, the aspirin or active aspirin derivative may additionally or alternately have the enteric coating. In all embodiments, the drug having the enteric coating or enteric formulation is targeted for absorption in the small intestine or colon, or both the small intestine and the colon.

主权项

1. A method of sequentially administering an aspirin or active aspirin derivative and a COX-2 inhibitor for partitioned absorption, at least one of which has an enteric or partial enteric coating for bioabsorption in a patient's small intestine or colon.