| 摘要 |
PROBLEM TO BE SOLVED: To provide novel heteroaryl amide analogues as probes for the detection and localization of P2X7 receptors, pharmaceutical compositions comprising the compounds, and a use method thereof. ! SOLUTION: Disclosed are heteroaryl amide analogues of formula Ia and/or Ib. The heteroaryl amide analogues are agonists and/or ligands of dopamine receptors and may be useful, inter alia, for the treatment of a condition responsive to P2X7 receptor modulation, for example, pain, inflammation, a neurological or neurodegenerative disorder, a cardiovascular disorder, an ocular disorder or an immune system disorder. ! COPYRIGHT: (C)2015,JPO&INPIT |
