METHOD FOR MANUFACTURING GRANULES CONTAINING IMATINIB MONOMESYLATE α TYPE CRYSTAL, AND GRANULES CONTAINING THE α TYPE CRYSTAL AND TABLET CONTAINING THE GRANULES

摘要

PROBLEM TO BE SOLVED: To provide method for manufacturing a granules containing imatinib monomesylate α type crystal suitable for pharmaceutical process, and granules containing the α type crystal and a tablet containing the granules. ! SOLUTION: There is provided a method for manufacturing granules containing imatinib monomesylate α type crystal in which imatinib monomesylate crystal powder containing imatinib monomesylate α type crystal is stirred while hydrous ethanol or absolute ethanol having ethanol concentration of 65 mass % or more is added to the powder, and the powder is granulated by the stirring. ! COPYRIGHT: (C)2015,JPO&INPIT