发明名称 IMMUNOGLOBULIN-LIKE MOLECULES DIRECTED AGAINST FIBRONECTIN-EDA
摘要 The present invention is concerned with immunoglobulin (Ig)-like molecules or fragments thereof for use in treatment, prevention, or prevention of progression of adverse cardiac remodelling and conditions resulting from or relating to myocardial infarction and pressure-overload, such as heart failure, aneurysm formation and remote myocardial fibrosis and for use in improving angiogenesis, preferably after ischemic injury. The invention also provides nucleic acid molecules encoding said Ig-like molecules, vectors comprising same, and host cells comprising same.
申请公布号 CA2933471(A1) 申请公布日期 2015.06.18
申请号 CA20142933471 申请日期 2014.12.12
申请人 UMC UTRECHT HOLDING B.V. 发明人 ARSLAN, FATIH
分类号 C07K16/18;A61K31/7088;A61K35/12;A61K39/395;A61P9/10;C07K16/46;C12N5/10;C12N5/16;C12N15/13 主分类号 C07K16/18
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