发明名称 |
INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 |
摘要 |
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of lysine specific demethylase-1. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like. |
申请公布号 |
CA2933480(A1) |
申请公布日期 |
2015.06.18 |
申请号 |
CA20142933480 |
申请日期 |
2014.12.10 |
申请人 |
CELGENE QUANTICEL RESEARCH, INC. |
发明人 |
CHEN, YOUNG, K.;KANOUNI, TOUFIKE;KALDOR, STEPHEN W.;STAFFORD, JEFFREY ALAN;VEAL, JAMES MARVIN |
分类号 |
C07D471/04;A61K31/395;A61K31/416;A61K31/437;A61K31/454;A61K31/4545;A61K31/506;A61K31/5377;A61K31/5386;A61K31/55;A61P35/00;C07D401/12;C07D401/14;C07D403/12;C07D413/12;C07D471/10;C07D487/04;C07D487/10;C07D498/08 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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