发明名称 |
Compositions and methods for producing dendritic cells |
摘要 |
The present invention relates to compositions and methods for producing dendritic cells and particularly to compositions and methods for producing immature dendritic cells that are immunocompetent. We describe a method of producing dendritic cells by cultivation of monocytes, characterised by at least one of: pre-treatment of a tissue culture surface with at least one of: a substantially plasma-free and serum-free pre-treatment medium, a pre-treatment medium comprising heparin, and a pre-treatment medium comprising a protein solution; adsorption of monocytes using at least one of: a substantially plasma-free and serum-free adsorption medium; cultivation of monocytes using a substantially plasma-free and serum-free cultivation medium. We also describe compositions including the dentritic cells and uses of the dentritic cells. |
申请公布号 |
AU2011288416(B2) |
申请公布日期 |
2015.06.18 |
申请号 |
AU20110288416 |
申请日期 |
2011.08.11 |
申请人 |
CYTOVAC A/S |
发明人 |
KIRKIN, ALEXEI;DJANDJOUGAZIAN, KARINE;JENSEN, MARTIN ROLAND |
分类号 |
C12N5/0784 |
主分类号 |
C12N5/0784 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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