CARBONATE-CONTAINING COMPOSITION FOR INTRAORALLY DISINTEGRATING TABLET, AND INTRAORALLY DISINTEGRATING TABLET

摘要

The purpose of the present invention is to provide an intraorally disintegrating tablet that has excellent tablet hardness and disintegration properties even if containing a large amount of medicinal ingredient, and the like. A composition for an intraorally disintegrating tablet, said composition comprising a disintegrating granular composition that is produced by at least a two-step granulation method and a hydrogencarbonate; an intraorally disintegrating tablet containing a medicinal ingredient that has a partition coefficient of -6.0 to 10.0, in particular, the aforesaid intraorally disintegrating tablet wherein the disintegrating granular composition contains acid-type carboxymethylcellulose, the tablet hardness is 30 to 150 N, and the disintegration time in water is 10 to 25 sec; and the like.