发明名称 |
IMIDAZOTRIAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY |
摘要 |
A series of substituted imidazo[l,2-b][l,2,4]triazine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. |
申请公布号 |
WO2015086503(A1) |
申请公布日期 |
2015.06.18 |
申请号 |
WO2014EP76841 |
申请日期 |
2014.12.08 |
申请人 |
UCB BIOPHARMA SPRL |
发明人 |
BROOKINGS, DANIEL, CHRISTOPHER;BROWN, JULIEN ALISTAIR;JACKSON, VICTORIA, ELIZABETH;PORTER, JOHN ROBERT;QUINCEY, JOANNA, RACHEL |
分类号 |
C07D487/04;A61K31/5025 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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