发明名称 |
CORNEAL OPACIFICATION ANIMAL MODEL USING ALKALI BURN AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CORNEAL OPACIFICATION |
摘要 |
The present invention is capable of providing an animal model in which opacification has been effectively induced by creating an alkali burn by using strong bases on the central cornea of an animal, and medicine for treating corneal opacification, which is the largest cause of loss of sight, can be effectively screened by using an animal model having induced corneal opacification according to the present invention. Also, provided in the present invention is a pharmaceutical composition containing a chondrocyte-derived extracellular membrane (CDECM) for preventing or treating corneal opacification which has been verified through the animal model, and a method for screening a therapeutic agent for corneal opacification. |
申请公布号 |
WO2015088093(A1) |
申请公布日期 |
2015.06.18 |
申请号 |
WO2014KR00037 |
申请日期 |
2014.01.03 |
申请人 |
INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION |
发明人 |
YANG, JAE WOOK;LEE, HYE SOOK;LEE, YOON JIN;LEE, JI HYUN;KIM, CHAE EUN |
分类号 |
A01K67/027;A61K35/32;G01N33/15 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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