发明名称 |
METHODS AND COMPOSITIONS FOR THE RAPID PRODUCTION OF RETINAL PIGMENTED EPITHELIAL CELLS FROM PLURIPOTENT CELLS |
摘要 |
The invention relates to the field of cell culture, specifically, the derivation of retinal pigmented epithelial cells from pluripotent cells. The invention comprises the use of various cell culture medium supplements, medium formulations, and methods of using such medium supplements and formulations, in order to effect the rapid differentiation of pluripotent cells into retinal pigmented epithelial cells with very high yields. The invention further includes cell culture media formulations for the efficient maintenance, propagation, and maturation of cultured retinal pigmented epithelial cells. |
申请公布号 |
EP2882846(A1) |
申请公布日期 |
2015.06.17 |
申请号 |
EP20130799830 |
申请日期 |
2013.06.05 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
CLEGG, DENNIS;BUCHHOLZ, DAVID;CROZE, ROXANNE;PENNINGTON, BRITNEY;COFFEY, PETER;LEACH, LYNDSAY |
分类号 |
C12N5/02;C12N5/079;C12N5/0793 |
主分类号 |
C12N5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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