发明名称 |
METHODS OF MANUFACTURING HYDROGEL MICROPARTICLES HAVING LIVING CELLS, AND COMPOSITIONS FOR MANUFACTURING A SCAFFOLD FOR TISSUE ENGINEERING |
摘要 |
Method of manufacturing hydrogel microparticles comprising one or more species of living cells attached thereon and/or encapsulated therein is provided. The method includes dissolving a hydrogel-forming agent in an aqueous medium to form a solution; suspending one or more species of living cells in the solution to form a cell suspension; dispersing the cell suspension into an organic oil to form a microemulsion; and subjecting the microemulsion to conditions that allow the hydrogel-forming agent to form hydrogel microparticles comprising one or more species of living cells attached thereon and/or encapsulated therein. Composition comprising a mixture of a degradable hydrogel and at least one hydrogel microparticle having one or more species of living cells, and method of manufacturing a scaffold for tissue engineering are also provided. |
申请公布号 |
EP2882465(A1) |
申请公布日期 |
2015.06.17 |
申请号 |
EP20130828142 |
申请日期 |
2013.07.26 |
申请人 |
NANYANG TECHNOLOGICAL UNIVERSITY |
发明人 |
WANG, DONGAN;LAU, TING TING;LEONG, WENYAN |
分类号 |
A61L27/52;A61L27/14;A61L27/22;A61L27/38;A61L27/56 |
主分类号 |
A61L27/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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