| 发明名称 |
ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE |
| 摘要 |
<p>The present invention relates to compounds of formula I or a pharmaceutically acceptable salt thereof, wherein A1, A2, A3, L1, L2 and D are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the Compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.</p> |
| 申请公布号 |
EP2734516(B1) |
申请公布日期 |
2015.06.17 |
| 申请号 |
EP20120738366 |
申请日期 |
2012.07.17 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
HEIM-RIETHER, ALEXANDER;LIANG, SHUANG;PADYANA, ANIL KUMAR;TAYLOR, STEVEN JOHN;ZHANG, QIANG |
| 分类号 |
C07D401/12;A61K31/415;A61K31/4155;A61P9/00;C07D231/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D471/04;C07D513/04 |
主分类号 |
C07D401/12 |
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