猪生殖与呼吸道症候群病毒、组合物、疫苗及使用方法;PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, COMPOSITIONS, VACCINE AND METHODS OF USE

摘要

本发明系关于具有增加稳定性之猪生殖与呼吸道症候群病毒(PRRSV)突变株；含有病毒株或其所衍生之抗原之组合物；含有该等病毒株之疫苗，包括灭活、减毒或次单位疫苗；编码PRRSV多肽之核酸、由该等核酸编码之多肽，包括其抗原片段；与该等多肽特异性结合之抗体，及其制造与使用方法。; compositions containing the strains or antigens derived therefrom; vaccines containing the strains, including killed, attenuated or subunit vaccines; nucleic acids encoding PRRSV polypeptides, polypeptides encoded by the nucleic acids, including antigenic fragments thereof; antibodies which specifically bind to said polypeptides, and methods making and using thereof.