| 摘要 |
<p>The present invention relates to a solid pharmaceutical product provided in the form of a suppository which comprises a photosensitiser which is a 5-ALA ester of general formula I, or a pharmaceutically acceptable salt thereof:
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ R 2 2 N-CH 2 COCH 2 -CH 2 CO-OR 1 €ƒ€ƒ€ƒ€ƒ€ƒ(I)
(wherein
R 1 represents a substituted or unsubstituted, straight-chained, branched or cyclic alkyl group; and
each R 2 independently represents a hydrogen atom);
and at least one pharmaceutically acceptable carrier or excipient which is a hard fat or a mixture of hard fat and additives. The pharmaceutical product may be used in the photodynamic treatment of cancer, and infections associated with cancer, and in the treatment of non-cancerous conditions, in particular in treating cancerous or non-cancerous conditions in the female reproductive system, for example cervical cancer and infections caused by the human papillomavirus.</p> |
