Compositions and methods for treating viral diseases

摘要

Substituted perhydro pyrrolopyridines and methods for their use in the treatment of viral diseases including hepatitis C viral infections are described herein.

主权项

1. A method for treating a patient having hepatitis C, the method comprising the step of administering to the patient a therapeutically effective amount of one or more compounds of the formulaor a pharmaceutically acceptable salt thereof, wherein:
R1 is arylalkyl or arylacyl, each of which is optionally substituted; R2 is hydrogen, alkyl, heteroalkyl, cycloalkyl, cycloheteroalkyl, aryl, or arylalkyl, each of which is optionally substituted; R3 is arylalkyl or arylacyl, each of which is optionally substituted; and R4 is hydrogen, alkyl, heteroalkyl, cycloalkyl, cycloheteroalkyl, aryl, or arylalkyl, each of which is optionally substituted, alone or as a composition with one or more carriers, diluents, or excipients, or a combination thereof.