Unit dose formulation of antidotes for factor Xa inhibitors and methods of using the same

摘要

The present invention relates unit dose formulations of antidotes to anticoagulants targeting factor Xa. Disclosed herein are methods of stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor.

主权项

1. A unit dose formulation consisting essentially of a pharmaceutically acceptable carrier and from about 200 milligrams to about 1 gram of a two-chain polypeptide comprising the amino acid sequence of SEQ ID NO. 13.