治疗及预防缺血性伤害之组成物与方法;COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING ISCHEMIC INJURY

摘要

本揭示案系关于一种用于治疗及预防缺血性伤害的组成物。更特定言之，本揭示案系关于一种含有衍生自端粒酶之胜肽的组成物，该组成物对治疗及预防缺血性伤害有效。;根据本揭示案的胜肽、具有与胜肽之胺基酸序列80%或以上之序列同源性的胜肽或系上述之片段的胜肽对治疗及预防缺血性伤害具有优良效果。因此，含有胜肽的组成物可有效用于缺血性伤害，尤其是用于缺血性-再灌注伤害。;The peptide according to the present disclosure, a peptide having 80% or more sequence identity with the amino acid sequence of the peptide or a peptide which is a fragment thereof has a superior effect of treating and preventing an ischemic injury. Accordingly, a composition containing the peptide may be effectively used for an ischemic injury, particularly for an ischemic-reperfusion injury.