发明名称 Composto derivado de 5-aminociclometil-oxazondin-2-ona, medicamento e composição farmacêutica que os contém e uso dos mesmos
摘要 The invention relates to antibacterial compounds of formula I wherein one or two of U, V, W, and X represent N, the rest represent CH or, in the case of X, may also represent CRa wherein Ra is fluorine; R1 represents alkoxy, halogen or cyano; R2 represents H, CH2OH, CH2N3, CH2NH2, alkylcarbonylaminomethyl or triazol-1-ylmethyl; R3 represents H, or, when n is 1, R3 may also represent OH, NH2, NHCOR6 or triazol-1-yl; A represents CR4; K represents O, NH, OCH2, NHCO, NHCH2, CH2NH, CH2CH2, CH═CH, CHOHCHOH or CHR5; R4 represents H or together with R5 forms a bond, or also R4 can represent OH when K is not O, NH, OCH2 or NHCO; R5 represents OH or together with R4 forms a bond; R6 represents alkyl; m is 0 or 1 and n is 0 or 1; and G is as defined in the description; and to salts of such compounds.
申请公布号 BRPI0820985(A2) 申请公布日期 2015.06.16
申请号 BR2008PI20985 申请日期 2008.12.17
申请人 ACTELION PHARMACEUTICALS LTD 发明人 CHRISTIAN HUBSCHWERLEN;GEORG RUEEDI;JEAN-PHILIPPE SURIVET;CORNELIA ZUNBRUNN ACKLIN
分类号 C07D413/14;A61K31/435;A61K31/4375;A61K31/517;A61K31/536;A61K31/5415;A61P31/00;C07D417/14;C07D471/04 主分类号 C07D413/14
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