发明名称 |
Ciclopentanos de pirimidila como inibidores de proteína quinase akt |
摘要 |
<p>The present invention provides compounds of Formula I , including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.</p> |
申请公布号 |
BRPI0813993(A2) |
申请公布日期 |
2015.06.16 |
申请号 |
BR2008PI13993 |
申请日期 |
2008.07.03 |
申请人 |
ARRAY BIOPHARMA INC.;GENENTECH, INC. |
发明人 |
JOSEF BENCSIK;JAMES F. BLAKE;NICHOLAS C. KALLAN;IAN S. MITCHELL;KEITH L. SPENCER;DENGMING XIAO;RUI XU;CHRISTINE CHABOT;JUN LIANG;BRIAN S. SAFINA |
分类号 |
C07D239/70;A61K31/517;A61P35/00 |
主分类号 |
C07D239/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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