Spectral imaging

摘要

A method includes concurrently modulating administration of at least two different contrast agents to a subject during an imaging procedure based on a modulation profile. The at least two different contrast agents exhibit different spectral characteristics. The method further includes performing a spectral decomposition of data indicative of the at least two different contrast agents, determining concentrations of the at least two different contrast agents based on the spectral reconstruction, and determining a perfusion parameter based on a ratio of the concentrations and the modulation profile.

主权项

1. A method, comprising:
performing a perfusion imaging procedure with a computed tomography scanner while concurrently modulating administration of at least two different contrast agents to a same vessel of a subject during the imaging procedure based on a modulation profile, wherein the at least two different contrast agents exhibit different spectral characteristics; generating time series perfusion volumetric image data indicative of the at least two different contrast agents; performing a spectral decomposition of the time series perfusion volumetric image; determining concentrations of the at least two different contrast agents for an image of the time series perfusion volumetric image data based on the spectral decomposition; determining a ratio of the concentrations; mapping the ration of the concentrations to a time of the ratio in the modulation profile at which the at least two different contrast agents were administered with the ratio in the modulation profile; and determining a perfusion parameter based on the mapping time between the ratio of the concentrations and the modulation profile.