发明名称 |
Composto, processo para preparar o mesmo, composição farmacêutica, processo para preparar a mesma, uso de um composto, e, método para tratar, ou reduzir o risco de, uma doença ou condição. |
摘要 |
<p>The invention provides compounds of formula (I) wherein R1, R3, L1, L2, G1, G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.</p> |
申请公布号 |
BRPI0821299(A2) |
申请公布日期 |
2015.06.16 |
申请号 |
BR2008PI21299 |
申请日期 |
2008.12.18 |
申请人 |
ASTRAZENECA AB |
发明人 |
JOHAN BYLUND;MARIA E. EK;YLVA GRAVENFORS;JÖRG HOLENZ;ALEXANDER MINIDIS;GUNNAR NORDVALL;DANIEL SOHN;KARL S. A. VALLIN;JENNY VIKLUND;STEFAN VON BERG |
分类号 |
C07D307/79;A61K31/18;A61K31/341;A61K31/343;A61K31/381;A61K31/404;A61K31/4155;A61K31/4245;A61K31/426;A61K31/4402;A61K31/4418;A61K31/505;A61P29/00;C07C311/44;C07D209/10;C07D213/30;C07D213/64;C07D233/96;C07D271/10;C07D277/32;C07D307/10;C07D307/38;C07D333/34;C07D333/76;C07D409/04 |
主分类号 |
C07D307/79 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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