发明名称 |
PYRROLIDINONE, PYRROLIDINE-2,5-DIONE, PYRROLIDINE AND THIOSUCCINIMIDE DERIVATIVES, COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER |
摘要 |
<p>The present invention relates to pyrrolidin-2-one, pyrrolidin-2, 5-dione, pyrrolidine and thiosucciniroide compounds of formulae (I) - (IV), and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidin-2-one, pyrrolidin-2, 5-dione, pyrrolidine and thiosuccinimide compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of pyrrolidin-2-one, pyrrolidin-2, 5-dione, pyrrolidine and thiosuccinimide compound of the present invention.</p> |
申请公布号 |
CA2690799(C) |
申请公布日期 |
2015.06.16 |
申请号 |
CA20082690799 |
申请日期 |
2008.06.19 |
申请人 |
ARQULE, INC. |
发明人 |
WANG, JIANQIANG;ALI, SYED M.;KELLEHER, EUGENE;LIU, YANBIN;HILL, JASON;ASHWELL, MARK A. |
分类号 |
C07D403/14;A61K31/404;A61P35/00 |
主分类号 |
C07D403/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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