YEAST CELL WITH INACTIVATED GLYCEROL-3-PHOSPHATE DEHYDROGENASE AND ACTIVATED GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE AND METHOD OF PRODUCING LACTATE USING THE SAME

摘要

Provided are a yeast cell with improved lactate productivity; and a method for producing lactate using the same. According to an embodiment of the present invention, the yeast cell has inactivated or reduced glycerol-3-phosphate dehydrogenase activity which converts dihydroxyacetone phosphate to glycerol-3-phosphate and increased glyceraldehyde-3-phosphate dehydrogenase activity converting glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate.