PPM QUANTIFICATION OF IODATE USING PAPER DEVICE

摘要

A highly sensitive method that utilizes a Paper Analytical Device (PAD) which measures part per million (ppm) levels of iodate iodometric titration is provided. The PAD quantifies concentrations of 0.6-15 parts per million (ppm) of iodine. The PAD has at least 12 reaction zones that contain dried reagents thereon and at least one electronically readable information zone. Salt and water are mixed and drops are placed onto 12 reaction zones that contain the loaded dry reagents. The PAD is shaken and the reaction zones turn blue if a preset iodate concentration has been exceeded. Test results are analyzed by comparing the PAD or an image of the PAD with standards, either by eye or with image analysis software to measure the color intensities which are compared to a calibration curve to quantify the iodate levels. The image analysis quantifies iodine with an average absolute accuracy and precision of 0.9 ppm over a range of 0.6-15 ppm.

主权项

1. A paper analytical device for detection of part per million levels of iodide and quantification of part per million levels of iodate by iodometric titration comprising:
a porous hydrophilic medium; a plurality of reaction zones associated with the porous hydrophilic medium; at least one assay reagent which has been deposited and dried onto each of the at least reaction zones; at least one electronically readable information zone which provides a color information for the detection and quantitation of part per million levels of iodate in fortified salt when a predetermined solution of the salt has been applied onto the reaction zones, wherein the at least one electronically readable information zone comprises a plurality of fiducial markers for correct alignment of the paper analytical device for transforming and correcting a captured image such that analysis and processing of the color information to more accurately quantitate part per million levels of iodate is efficiently afforded.