| 发明名称 |
SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1 -[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYTALLINE FORMS THEREOF |
| 摘要 |
The present invention provides processes to manufacture substituted l-[4-(Pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10b- tetraaza-benzo[e]azulenes. Also disclosed are compounds useful as intermediates in the methods of the invention. |
| 申请公布号 |
WO2015082370(A1) |
申请公布日期 |
2015.06.11 |
| 申请号 |
WO2014EP76041 |
申请日期 |
2014.12.01 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. |
发明人 |
ROTHENHAEUSLER, BENNO;TRUSSARDI, RENÉ;HOFFMANN-EMERY, FABIENNE;SCHWITTER, URS;ADAM, JEAN-MICHEL;GRASSMANN, OLAF;HARTUNG, THOMAS;RAN, FREDERIC;DIODONE, RALPH;PFLEGER, CHRISTOPHE;BARTELS, BJOERN |
| 分类号 |
C07D487/04;A61K31/5517;A61P25/00 |
主分类号 |
C07D487/04 |
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