Dlg1/SAP97 GENE SPLICING VARIANT, AND DETECTION OF SCHIZOPHRENIA USING SPLICING VARIANT

摘要

Provided are a novel splicing variant of a Dlg1/SAP97 gene associated with schizophrenia, and a method for evaluating the risk of schizophrenia by measuring the expression level of the splicing variant. The method for evaluating the risk of schizophrenia includes measuring the expression level of a splicing variant expressed by an exon (3b) being inserted between an exon (3a) of the Dlg1/SAP97 gene and an exon (4). The risk of schizophrenia is evaluated as high when the expression level of the splicing variant in a healthy subject is comparatively low, and the risk of schizophrenia is evaluated as low when the expression level in the healthy subject is comparatively high.