发明名称 |
DETERMINATION OF THE UNBOUND FREE FATTY ACID PROFILES IN BIOLOGICAL AND INDUSTRIAL SPECIMENS |
摘要 |
A method for high throughput discovery of proteins fluorescently labeled at a cysteine residue and that undergo a change in fluorescence ratio at 2 wavelengths upon binding an unbound analyte is described. Probes are disclosed which are labeled at a cysteine residue and also probes labeled at both cysteine and lysine with two different fluorophores. These probes are useful for characterization and measurement of hydrophobic species in a fluid sample, particularly characterization and measurement of levels of unbound free fatty acids. A profile of unbound free fatty acids can be determined for an individual which can be used to determine the individual's relative risk for disease. |
申请公布号 |
WO2015084894(A1) |
申请公布日期 |
2015.06.11 |
申请号 |
WO2014US68240 |
申请日期 |
2014.12.02 |
申请人 |
KLEINFELD, ALAN |
发明人 |
KLEINFELD, ALAN;HUBER, ANDREW |
分类号 |
G01N33/92;G01N33/52;G01N33/533;G01N33/68 |
主分类号 |
G01N33/92 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|