FRICTIONAL TRANS-EPITHELIAL TISSUE DISRUPTION AND COLLECTION APPARATUS AND METHOD OF INDUCING OR AUGMENTING AN IMMUNE RESPONSE

摘要

The invention relates to trans-epithelial frictionally abrasive tissue sampling devices for performing biopsies and methods of inducing an immune response against a pathogen, wherein epithelial cells containing the pathogen are disrupted with the frictionally abrasive tissue sampling device to introduce the pathogen into the bloodstream of a patient.

主权项

1. A method of inducing or augmenting an immune response comprising:
frictionally disrupting epithelial cells containing a pathogen with an apparatus for obtaining a histological sample comprising:
a handle;a platform at a distal end of the handle; anda fabric attached to the platform; and thereby eliciting an immune response.